FIELDS OF MEDICINE

IVF

Did You Know That?

Israel has carried out the greatest percentage of IVF procedures relative to its population, in the world. Israeli specialists have extensive experience working with innovative technologies in this field and have demonstrated positive results even in the most difficult of cases.

Few people know that most often the problem in making a baby lies in the sperm. Many different abnormalities impair the sperm cells ability to fertilize an egg. However, modern advances in male fertility allow couples that had previously had very little or even no real chance of getting pregnant, to do so.

Even if the percentage of normal sperm cells are less than one percent, new technology allows for very high accuracy sperm cell selections carried out under a magnification of 6000x. This, allows doctors to pick out those sperm cells, with the highest quality nucleus structure and therefore the highest potential of fertilizing an egg.

This technology coupled with advances in female fertility, allow almost any couple with any number of problems on either or even both sides, to have the ability to parent a child.

In recent years, as technology becomes evermore innovative and effective, the number of rounds of artificial insemination that future mothers have to endure on average before getting pregnant, has decreased significantly, meaning that the effectiveness of the procedures has dramatically increased.

 

What’s new in the field of IVF?

Israel has recently become proficient in such innovative technologies as:

  1. Embryoscope
  2. PDG
  3. IMSI

 

Embryoscope – One of the latest developments in the field of IVF is a unique incubator called an embryoscope. In the past, an embryo was grown in the laboratory for 2-3 days and inserted into the uterus before developing into a blastocyst, with the hope that it would continue to evolve on its own and attach to the uterine wall. Now in Israel, the embryo is grown in this special incubator until the stage of becoming a blastocyst. This new technology not only provides optimal conditions for the growth of the embryo and its transformation into a blastocyst before the stage of implanting but also allows uninterrupted microscopic observation without the need for removal from the incubator.

 

PDG (pre-implantation genetic diagnosis) – In the field of prenatal diagnostics, one of the most important new innovative methods is the PGD (pre-implantation genetic diagnosis). This technology allows for the diagnosis of the embryo before the implantation into the uterus. (PDG) can diagnose fetal cells obtained by artificial insemination to identify or rule out possible genetic mutations or carrier mutations and verify the viability of the embryo. PGD reveals genetic abnormalities such as:

  1. Cystic fibrosis,
  2. Deafness
  3. Beta-thalassemia
  4. Myopathy
  5. Adrenoleukodystrophy
  6. Becker muscular dystrophy
  7. Duchenne
  8. Congenital cerebellar ataxia
  9. Hirschsprung’s disease
  10. Spastic paralysis
  11. Hemophilia

And the list goes on…

The list of detectable disease is constantly updated thanks to the development of the genetic and molecular fields of medicine and the ​​results or the test are known within 3-5 days after the egg retrieval, which enables the timely return of healthy embryos.

Some of the indications for the need to do a PDG exam can be:

  1. The older age of couple. (Over 35)
  2. A family history of genetic disorders
  3. Multiple miscarriages
  4. Failed IVF attempts.

 

IMSI (Intracytoplasmic morphologically selected sperm injection) – IMSI is an extremely important development in the field of IVF in cases where the problem of conceiving a child lies in the sperm. Scientists have discovered and documented the ideal proportions for a sperm cell with these proportions being those that have the greatest probability of fertilizing an egg. In cases where the percentage of sperm cells with a “normal” morphology is significantly lower than desirable, scientists, using a special microscope with a magnification of 15x that which is normally used, select several sperm cells with the ideal morphology and inject them into healthy eggs. This procedure is especially useful in cases where several rounds of IVF procedures prove to be unsuccessful.

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